Tina Köstler

Short Vita:

Education:

2008: University of applied sciences (FH) - Bioinformatics
2004: HTL Braunau - Mechatronics, Matura

Professional Experience:

05/2012-present: Postdoc at the Center for Integrative Bioinformatics Vienna (CIBIV)
11/2008-04/2012: PhD student at the Center for Integrative Bioinformatics Vienna (CIBIV)
01/2008-06/2008: Diploma student at the Center for Integrative Bioinformatics Vienna (CIBIV)
08/2007-01/2008: Internship at the Stockholm Bioinformatics Center (SBC)

Degree:

'Dr.rer.nat' (2012), Vienna
Thesis: Domains, Proteins, and Evolution.
'DI (FH)' (2008), Hagenberg
Thesis: Identification of Golgins in Trypanosma brucei.

Publications

J. Loidl, A. Lukaszewicz, R.A. Howard-Till, T.Koestler (2012) The Tetrahymena meiotic chromosome bouquet is organized by centromeres and promotes interhomolog recombination. Journal of Cell Science,125, in press (DOI: 10.1242/jsc.112664))
T. Koestler (2012) Domains, Proteins, and Evolution. PhD thesis
T. Koestler, A. von Haeseler, I. Ebersberger (2012) REvolver: Modeling sequence evolution under domain constraints. Molecular Biology and Evolution, 29: 2133-2145 (DOI: 10.1093/molbev/mss078, PMID: 2383532)
C. Dessimoz, T. Gabaldón, D. S. Roos, E. Sonnhammer, J. Herrero, and the Quest for Orthologs Consortium* (2012) Toward Community Standards in the Quest for Orthologs. Bioinformatics, 28:6 (pp.900-904) (DOI: 10.1093/bioinformatics/bts050 , PMID: 22332236)
*Members of the Quest for Orthologs Consortium: Adrian Altenhoff, Rolf Apweiler, Judith Blake, Brigitte Boeckmann, Alan Bridge, Elspeth Bruford, Mike Cherry, Matthieu Conte, Durand Dannie, Ruchira Datta, Jean-Baka Domelevo Entfellner, Ingo Ebersberger, Michael Galperin, Jacob Joseph, Tina Koestler, Evgenia Kriventseva, Odile Lecompte, Jack Leunissen, Suzanna Lewis, Benjamin Linard, Michael S. Livstone, Hui-Chun Lu, Maria Martin, Raja Mazumder, Vincent Miele, Matthieu Muffato, Guy Perriere, Marco Punta, Mathieu Rouard, Thomas Schmitt, Fabian Schreiber, Alan Silva, Kimmen Sjölander, Nives Skunca, Eleanor Stanley, Radek Szklarczyk, Paul Thomas, Ikuo Uchiyama, Michiel Van Bel, Klaas Vandepoele, Albert J. Vilella, Andrew Yates, and Evgeny Zdobnov.
T. Koestler and I. Ebersberger (2011) Zygomycetes, microsporidia, and the evolutionary ancestry of sex determination. Genome Biology and Evolution 3: 186-194. (DOI: 10.1093/gbe/evr009, PMID: 21307298)
T. Koestler, A. von Haeseler, and I. Ebersberger (2010) FACT: Functional annotation transfer between proteins with similar feature architecture. BMC Bioinformatics, 11(1):417 (DOI: 10.1186/1471-2105-11-417,PMID: 20696036)
Ostlund G, Schmitt T, Forslund K, Köstler T, Messina DN, Roopra S, Frings O, Sonnhammer EL. (2010) InParanoid 7: new algorithms and tools for eukaryotic orthology analysis. Nucleic Acids Res., 38(Database issue):D196-203 (DOI: 10.1093/nar/gkp931, PMID: 19892828)

Talks

REvolver: Modeling sequence evolution under domain constraints
Mechanisms of Protein Evolution 2012, Denver, USA, December 5-7, 2011. (program)
REvolver: Modeling sequence evolution under domain constraints
Annual Meeting of the Society for Molecular Biology and Evolution (SMBE 2011), Kyoto, Japan, July 26-30, 2011. (program)
First steps to assess the evolutionary traceability of proteins
Quest for Orthologs Workshop 2011 (program), Hinxton, Cambridge, UK, 17.-19.06.2011
Simulating sequence evolution under domain constraints
Young Investigators Day: Computational Life Sciences, Vienna, Austria, 03.02.2011
Simulating sequence evolution under domain constraints
Deep Metazoan Phylogeny: Statusseminar, Hannover, Germany, 28.01-29.01.2011
Searching for functional equivalent proteins at the feature architecture level
11th International EMBL PhD Student Symposium: Puzzles in Biology - putting the pieces together, Heidelberg, Germany, 29.10.-31.10.2009

Poster

How stable are protein domains in the course of evoluton?
Annual Meeting of the Society for Molecular Biology and Evolution (SMBE 2012), Dublin, Irland, 23.6.-26.6.2012. (program)
Feature architecture similarity complements sequence similarity in tracing the evolution of functional protein complexes
Annual Meeting of the Society for Molecular Biology and Evolution (SMBE 2010), Lyon, France, 4.7.-8.7.2010. (program)

Tools

Workshops

Computational Molecular Evolution
Wellcome Trust Genome Campus, Hinxton, Cambridge, UK, 10-21 April 2011
Evolutionary Genetics Workshop
IST Austria, 27.09.2010 - 01.10.2010

Addresses

Tina Köstler

Center for Integrative Bioinformatics Vienna (CIBIV)
(CIBIV is a joint institute of Vienna University, and Medical University, Vienna, Austria)
Max F. Perutz Laboratories (MFPL)
Campus Vienna Biocenter 5 (VBC5), Ebene 1, Room 1812.3
A-1030 Wien, Austria
Phone: ++43 +1 / 4277 24027
Fax: ++43 +1 / 4277 24098
Email: tina.koestler(AT)univie.ac.at

Postal Address:

Center for Integrative Bioinformatics Vienna (CIBIV)
Max F. Perutz Laboratories (MFPL)
Campus Vienna Biocenter 5 (VBC5), Ebene 1, Room 1812.3
A-1030 Wien, Austria

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