Center for Integrative Bioinformatics Vienna
Max F. Perutz Laboratories
Dr. Bohr Gasse 9
A-1030 Vienna, Austria
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   Max F. Perutz Laboratories
   University of Vienna
   Medical University, Vienna

   Deep Metazoan Phylogeny
   MaBS group
   Max Perutz Library
Fritz Sedlazeck

Fritz Sedlazeck

Research Interests:

In general, my interests focus on three key areas:
  • Sequence Analysis:
      Processing Next Generation Sequencing (NGS) data
      Developing programs and methods to analyse NGS data
  • Structure prediction:
      Algorithms for computational and structural biology
      Visualizations of macro molecular structures
      Integration of sequence information and structural prediction
  • High performance computing:
      Programming on GPU Graphics Cards (CUDA, OpenCL)
      Programming on CPUs (SSE)

Short Vita:


  • 2012: Dr. rer. nat. Bioinformatics
  • 2008: Diplom (FH) Bioinformatics
  • 2003: Abitur

Professional Experience:

  • December 2012 - December 2014: Post Doc at the Center for Integrative Bioinformatics Vienna (CIBIV)
  • September 2008 - December 2012: PhD student at the Center for Integrative Bioinformatics Vienna (CIBIV)
  • September 2007 - June 2008: EMBL Heidelberg, Frangakis Group


  • 'Ph.D' in Molecular Biology (Dr. rer. nat.), Vienna, Austria, 2012
    Thesis: Benchtop sequencing on benchtop computers.
  • DI (FH) (2008), Hagenberg
    Thesis: Correlative Cryo-Fluorescence and cryo-Electron Microscopy.

Fellowships, Fundings, and Awards:

  • Leonardo da Vinci II Traineeship (2007)
  • Vienna Biocenter PhD Award (2013)


  • C. Vesely, S. Tauber, F. Sedlazeck, M. Tajaddod, A. von Haeseler, and M. Jantsch (2014) ADAR2 induces reproducible changes in sequence and abundance of mature microRNAs in the mouse brain. Nucleic Acids Res., in press. (DOI: 10.1093/nar/gku844, PMID: 25260591)
  • F.J. Sedlazecke, P. Reschenedere, and A. von Haeseler (2013) NextGenMap: Fast and accurate read mapping in highly polymorphic genomes. Bioinformatics, 29, 2790-2791. (DOI: 10.1093/bioinformatics/btt468, PMID: 23975764).

  • S. Jünemann, F.J. Sedlazeck, K. Prior, A. Albersmeier, U. John, J. Kalinowski, A. Mellmann, A. Goesmann, A. von Haeseler, J. Stoye and D. Harmsen (2013) Updating benchtop sequencing performance comparison. Nat. Biotechnol., 31, 294-296. (DOI: 10.1038/nbt.2522, PMID: 23563421)

  • F.J. Sedlazeck, P. Talloji, A. von Haeseler, and A. Bachmair (2013) Benefit-of-doubt (BOD) scoring: a sequencing-based method for SNP candidate assessment from high to medium read number data sets. Genomics, 101, 204-209. (DOI: 10.1016/j.ygeno.2012.12.001, PMID: 23246509)
  • H.Q. Dinh, M. Dubine, F.J. Sedlazecke, N. Lettner, O. Mittelsten Scheid, and A. von Haeseler (2012) Advanced Methylome Analysis after Bisulfite Deep Sequencing: an Example in Arabidopsis. PLoS ONE, 7, e41528. (DOI: 10.1371/journal.pone.0041528, PMCID: PMC3401099)

  • P. Rescheneder, A. von Haeseler, and F.J. Sedlazeck (2012) MASon: Million Alignments In Seconds - A Platform Independent Pairwise Sequence Alignment Library for Next Generation Sequencing Data. Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms (BIOINFORMATICS 2012), 195-201, SciTePress, Setubal, Portugal. (DOI: 10.5220/0003775701950201)

  • C. Veselye, S. Taubere, F.J. Sedlazeck, A. von Haeseler, and M.F. Jantsch (2012) Adenosine deaminases that act on RNA induce reproducible changes in abundance and sequence of embryonic miRNAs. Genome Res., 22, 1468-1476. (DOI: 10.1101/gr.133025.111, PMID: 22310477)

e contributed equally


Fritz Sedlazeck

Center for Integrative Bioinformatics Vienna (CIBIV)
(CIBIV is a joint institute of Vienna University, and Medical University, Vienna, Austria)
Max F. Perutz Laboratories (MFPL)
Dr. Bohr Gasse 3 / 6.15
A-1030 Wien, Austria
Phone: ++43 +1 / 4277-24023
Fax: ++43 +1 / 79044-4551
Email: fritz.Sedlazeck(AT)univie.ac.at

Postal Address:

Center for Integrative Bioinformatics Vienna (CIBIV)
Max F. Perutz Laboratories (MFPL)
Dr. Bohr Gasse 9
A-1030 Wien, Austria

Fritz Sedlazeck - Last Change: 28.Sep.2015 .