Welcome!
FACT has been developed to search for proteins having the same or a similar function. The similarity between the feature architectures of two proteins, i.e., their arrangements of functional domains, secondary structure elements and compositional properties, is used as a proxy for their functional equivalence.
Currently you can choose between the following options:
- Compare On this webpage, you can provide the sequences of two proteins. FACT will annotate the features in both proteins and will display a comparison of the two feature architectures via the feature dot plot.
- Find functional equivalents On this webpage you can use a protein sequence as query to search for functional equivalents in a selected search proteome. FACT annotates the features in the query sequence and uses then a scoring function to identify the protein with the most similar feature architecture in the search proteomes.
java 1.5 (or higher) needs to be installed and enabled